Ankylosing spondylitis AS is an inflammatory form of arthritis that preferentially attacks the spine. Many people are under the impression it’s one of the less serious forms of arthritis. Uhuh. Unfortunately, it has a number of potential complications associated with it. These include Acute eye inflammation, termed uveitis , in onethird of patients. Symptoms include pain, redness, blurred vision, light sensitivity, and if left untreated, blindness. 1. Osteoporosis occurring in a significant number of patients. This is a condition where the bones become brittle and more likely to fracture. 2. Approximately 1015 of patients have inflammatory bowel disease such as Crohn’s or ulcerative.